Cart
sales@molnova.com
Home - Products - Endocrinology/Hormones - Androgen Receptor (AR) - Enzalutamide carboxylic acid

Enzalutamide carboxylic acid

CAS No. 1242137-15-0

Enzalutamide carboxylic acid( —— )

Catalog No. M21564 CAS No. 1242137-15-0

Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 77 Get Quote
5MG 115 Get Quote
10MG 177 Get Quote
25MG 299 Get Quote
50MG 417 Get Quote
100MG 615 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Enzalutamide carboxylic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
  • Description
    Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
  • In Vitro
    Enzalutamide is converted into its major metabolites, N-desmethyl enzalutamide and carboxylic acid enzalutamide, by cytochrome P450 (CYP) 3A4/5 and CYP2C8, respectively. N-desmethyl enzalutamide has clinically relevant anti-androgen capacities similar to enzalutamide, whereas carboxylic acid enzalutamide is inactive.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    Androgen Receptor (AR)
  • Recptor
    Androgen Receptor
  • Research Area
    cancer
  • Indication
    castration-resistant prostate cancer

Chemical Information

  • CAS Number
    1242137-15-0
  • Formula Weight
    451.4
  • Molecular Formula
    C20H13F4N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (276.92 mM)
  • SMILES
    CC1(C)N(C(=S)N(C1=O)c1ccc(C#N)c(c1)C(F)(F)F)c1ccc(C(O)=O)c(F)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.van Nuland M et al. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy. 2019 Dec;39(12):1137-1145.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Enobosarm

    Enobosarm (GTx-024, MK-2866, Ostarine) is a selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and osteoporosis.

  • BMS-564929

    BMS-564929 is a potent, selective androgen receptor modulator (SARM) that binds to AR with Ki of 2.11 nM.

  • ORM-15341

    The active main metabolite of ODM-201, a potent wt/mutant androgen receptor (AR) inhibitor.

Sign In Join Free